Friendly, physician-guided medical weight loss

Start your weight loss journey with a team that truly follows through.

Supervised GLP-1 programs with safe titration, micro-dosing options, and side-effect support — designed for real, sustainable results.

Physician-supervised GLP-1 care

Medical oversight with consistent follow-ups.

Safe titration & micro-dosing

Designed to reduce side effects and plateaus.

Compounded options + B6*

May help reduce nausea and vomiting.

Nutrition & lifestyle coaching

Simple, realistic guidance that fits your life.

Progress tracking

Clear milestones and accountability.

Optional boosters

IV therapy, Lipo-B12, peptides, and more.

$200 OFF your first month with a 3–6 month plan commitment
★★★★★ Trusted by patients • Open daily 9 AM–9 PM • 21844 23 Mile Rd, Macomb, MI(586) 213-1492
*Compounded GLP-1 medications are not FDA-approved. They are prepared by licensed compounding pharmacies pursuant to federal and state law. Eligibility, medication type, and dosing are determined by medical evaluation. Results vary. Medical consultation required.
  • Meet with one of our licensed providers to review your goals, medical history, and determine if GLP-1 therapy may be right for you.

  • A focused clinical assessment is completed. Labs may be ordered when appropriate to ensure safety and eligibility

  • If approved, you’ll begin a provider-guided GLP-1 program, compounded with Vitamin B6, with safe dose titration based on your response

  • Receive weekly injections with continued follow-ups to monitor progress, manage side effects, and adjust dosing as needed

  • Ongoing nutrition guidance, lifestyle support, and regular check-ins to help you achieve sustainable results.

  • In addition to GLP-1 injections, patients may access advanced supportive therapies such as energy-boosting Lipo-B12 shots, B-LEAN IV infusions, hormone balancing (HRT), and peptide therapies — personalized to your goals.

  • All treatment plans are personalized based on your medical history, goals, and clinical evaluation. Individual results may vary and depend on factors such as adherence, lifestyle changes, and biological response to treatment. A medical consultation is required to determine eligibility, safety, and the most appropriate treatment plan for you.

Our Process

Work With Us

Program Eligibility and Our Process

Your first visit is designed to be informative, relaxed, and judgment-free. Our goal is to understand your goals, answer your questions, and determine the safest path forward — with no pressure to commit.

During your visit, you can expect:

✔️ A private conversation about your health history, lifestyle, and weight-loss goals
✔️ A clear explanation of GLP-1 medications, how they work, and what to expect
✔️ A discussion of potential benefits, side effects, and safety considerations
✔️ A review of program options, pricing, and next steps — no surprises
✔️ Time to ask questions and decide what feels right for you

⏱️ Most visits take approximately 30–45 minutes.

If appropriate, treatment may begin after your visit. If not, we’ll guide you toward the best next step for your health.

What to Expect at Your First Visit

Check Your BMI

Body Mass Index (BMI) is an estimate that uses your height and weight to help assess weight range for height. *

Height
ft
in
Weight
lbs

*BMI is an estimate. Eligibility for medical weight loss is determined during a medical consultation.

Your BMI
Underweight < 18.5
Healthy Weight 18.5–24.9
Overweight 25–29.9
Obesity 30+

Your Healthy Weight Range

Based on BMI 18.5–24.9 for your height
Estimated pounds to reach BMI 24.9

These are estimates for education only. Results vary and depend on individual factors and medical guidance.

✔️ Have a BMI ≥ 30
✔️ Have a BMI ≥ 27 with weight-related conditions
✔️ Have struggled to lose weight with diet and exercise alone
✔️ Are looking for safe, provider-led medical weight loss

⚠️ Final eligibility is determined during your medical consultation based on your health history, goals, and clinical evaluation.

Who Should Not Use GLP-1 Medications?

  • History of MTC or MEN 2

  • Pregnancy or breastfeeding

  • Severe GI conditions (e.g., gastroparesis)

  • Prior serious reaction to GLP-1 therapy

Eligibility and safety are determined during your medical consultation.

Who May Be a Candidate for GLP-1 Weight Loss?

Most Affordable & Comprehensive Weight Loss & Wellness program in Macomb

A vial labeled 'GLP-1 Injection' with apples and oranges in the background.

Essential GLP-1 Plan

Perfect for patients starting their weight-loss journey with safe, effective GLP-1 support.

Includes:

  • Detailed consultation (PMH, physical exam, and in-house labs if needed)

  • Personalized treatment plan tailored to your goals

  • Custom exercise & diet plan

  • Weekly GLP-1 injection

  • Significant discounts on wellness injections (Lipo-Mino B12, L-Carnitine, NAD+, Glutathione, Vitamin D, Peptides)

  • Weekly follow-ups, weight checks & dose adjustments

  • Ongoing provider support & progress monitoring

A small vial labeled 'GLP/GIP INJECTION' in front of a bowl of various apples.

Dual-Action GLP-1/GIP Plan

Enhanced metabolic support with the combination GLP-1/GIP medication for faster, stronger results.

Includes:

  • Everything from the Essential Package

  • Weekly GLP-1/GIP dual-therapy injection

  • Additional personalized adjustments to optimize faster weight loss

  • Priority access to providers for faster follow-up when needed

Three small glass vials labeled GLP-1 Injection, Lipo-B12 Injection, and NAD+ Injection, with a syringe labeled GLP-1 and a yellow insulin syringe, a red apple, and a yellow measuring tape on a white background.

Premium Plus Plan

GLP-1/GIP therapy + weekly wellness injection included (no extra charge) of your chocie. Perfect for patients who want accelerated results.

Includes:

  • Everything from the Dual-Action Package

  • Weekly wellness injection of your choice INCLUDED:

    • Lipo-Mino B12 (skinny shot)

    • L-Carnitine

    • NAD+

    • Vitamin D (MCT oil)

    • Glutathione

  • Expanded weekly goal tracking & coaching

Medical supplies including two vials labeled 'GLP-1/GIP' and 'NAD+', a glass IV bag with liquid, a rolled towel, lemon slices, fresh mint, and a measuring tape on a white marble table in a bright room.

Elite Transformation Plan

The most comprehensive program: dual-therapy medication + weekly wellness injection + monthly IV infusion + unlimited telemed follow-ups.

Includes:

  • Everything from the Premium Plus Package

  • Monthly IV vitamin infusion INCLUDED (NAD+, Glutathione, or custom blend)

  • Unlimited telemedicine follow-ups for ongoing adjustments & support

  • Highest level of accountability, monitoring, and custom guidance

Mention you saw this offer on our website and get $200 OFF your first month. (3-6 Month Plan)

More payment options available for your convenience such as full vial to do at home

A Weight Loss program your can trust

Disclaimer: Compounded medications are not FDA-approved; however, they are prepared by licensed compounding pharmacies in compliance with applicable state and federal regulations.

Why Choose Onyx for Weight Loss?

Comparison chart of Onyx Weight Loss & Wellness versus Typical Online Programs/Other Clinics, listing reasons for choosing Onyx such as affordable pricing, trust with real providers, personalized plans, FDA-registered medication, convenient hours, weekly check-ins, discounted wellness injections, IV therapy options, steady weight loss, and positive patient feedback.

Frequently asked questions and Honest Answers

How do GLP-1 medications work for weight loss?

1

We offer a range of solutions designed to meet your needs—whether you're just getting started or scaling something bigger. Everything is tailored to help you move forward with clarity and confidence.


Is GLP-1 weight loss a replacement for diet and exercise?

2

No. GLP-1 medications are designed to support, not replace, healthy lifestyle changes. They work best when combined with nutrition guidance, movement, and ongoing medical support — all of which are part of our program.


Why is gradual dose titration important?

3

Gradual dosing allows your body to adjust safely. It helps minimize common side effects, improves comfort, and ensures your treatment is personalized rather than rushed.


Why is Vitamin B6 included in the compounded medication?

4

Vitamin B6 is included to help improve tolerability and support comfort during treatment, particularly during dose adjustments. This is part of our provider-guided approach to managing side effects safely.


How soon will I notice changes?

5

Experiences vary. Some patients notice appetite changes early, while others see gradual progress over time. Our focus is steady, sustainable weight loss rather than rapid or extreme results.


What kind of monitoring is included?

6

Patients receive ongoing follow-ups with licensed providers to track progress, address side effects, and adjust treatment when needed. This ensures safety, accountability, and long-term success.


Can I stop treatment if I choose to?

7

Yes. Treatment decisions are always made collaboratively. Your provider will guide you on safe next steps if you decide to pause or discontinue treatment.

Real Patient Testimonials

  • “The team at Onyx made me feel supported every step of the way. The program was easy to follow, medically supervised, and the weekly check-ins really helped me stay consistent.”

    James E.

  • “I appreciated how medically supervised the program felt. The providers took time to explain everything, adjust dosing when needed, and check in weekly. I finally feel supported instead of rushed.”

    Amanda L.

  • “This isn’t a med spa or an online subscription. Having a real medical team monitoring my progress made all the difference.”

    Michael R.

  • “The process was straightforward, the staff was professional, and the support helped me stay consistent. I felt comfortable asking questions at every visit.”

    Jasmine K.

  • “What stood out to me was the accountability. The weekly check-ins and guidance helped me stay on track in a way I hadn’t experienced before.”

    Daniel S.

  • “I liked that everything was personalized. My provider adjusted my plan based on how I was feeling, not a one-size-fits-all approach.”

    Lauren M.

  • “From the first consultation, I felt listened to. The team focused on safety, education, and realistic expectations.”

    Robert T.